Test Code Test name and Information (one sentence only) Clinical Significance of the Test in Clinical Practice Method
MPA005 ADRB2 GENOTYPING FOR B-2-AGONIST RESPONSIVENESS To identify haplotypes of the ADRB2 gene that may have clinical implications for asthma severity, cardiovascular function, obesity, and response to beta-agonist PCR-Sequencing
MPA009 Alpha-1 Antitrypsin, Genotyping To confirm affected or carrier status in individuals with a serum AAT concentration less than 100 mg/dL. To determine affected or carrier status in individuals with a family history of AAT caused by the S or Z alleles.Prenatal diagnosis in foetuses, whose parents are both known carriers of the Z allele. PCR
MPC030 COMT (Catechol-O-methyltransferase )Genotyping Investigation of inhibitor dosing for decreasing L-DOPA metabolism. PCR-Sequencing
MPC033 Cytochrome P450 2C19 Genotype Dosing drugs that are metabolized by CYP2C19 may require adjustment based on the individual patient's genotype PCR
MPC036 Cytochrome P450 2D6 (CYP2D6) Pretherapeutic testing to identify individuals who should avoid or have different dosing of medications metabolized by CYP2D6 PCR
MPW001 Warfarin Sensitivity by Genotyping (CYP2C9*2,CYP2C9*3 &VKORC1) Aids in warfarin dosage planning in conjunction with VKORC1 testing. If individualized warfarin dosage recommendations are required. PCR-RFLP